Formulation: A solution in ethanol
Formal Name: N,N′,N′′-(nitrilotri-2,1-ethanediyl)tris[N-methyl-β-alanine, 1,1′,1′′-tridodecyl ester
Purity: ≥98%
Formula Markup: C54H108N4O6
Formula Weight: 909,5
Shelf life (days): 1460
CAS Number: 1566559-79-2
Notes: SIL lipid is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro.{67735} LNPs containing SIL lipid and encapsulating siRNA targeting mRNA encoding the purinergic P2X7 receptor decrease protein levels of the purinergic P2X7 receptor, reduce migration in a wound healing assay, and induce apoptosis and necrosis in 4T1 breast cancer cells.