SIRP-α (SIRP alpha), His-tag, Biotin-labeled (Human) HiP™ Recombinant

Products from BPS Bioscience require a minimum order value above 400€

Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 

Description: SIRP alpha protein, or Signal regulatory proteinalpha (SIRP-α), also known as Tyrosine protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal Avi and His tags, MW 40.3 kDa*, expressed in a HEK293 expression system and enzymatically biotinylated using Avi-tag™ technology. This SIRP alpha protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in higher molecular weight.

Formulation: 8 mM Na Phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol.

Genbank: NM_080792

Storage Stability: At least 6 months at -80°C.

Supplied As: Aqueous buffer solution.

Tags: C-terminal His-Avi-Tags

Uniprot: P78324

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77
2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63

• Artikelnummer: BPS71138-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71138-1
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK