Application Note: WB: 1:1000. IHC-P: 1:50-100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 44
Form: Liquid
Buffer (with preservative): PBS, 0.09% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene. [provided by RefSeq, Jul 2008]
Uniprot ID: Q9NTG7
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide between 250-279 amino acids from the C-terminal region of human SIRT3.
Purification: Protein A purified followed by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: sirtuin 3