Product Description: SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA[1].
Applications: Cancer-programmed cell death
Formula: C39H44N4O12
References: [1]S J Gregson, et al. Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicity. J Med Chem. 2001 Mar 1;44(5):737-48.
CAS Number: 232931-64-5
Molecular Weight: 760.79
Compound Purity: 99.95
Research Area: Others
Target: ADC Cytotoxin