SKF-96365, CAS 130495-35-1

TRPC channel blocker

Product Type: Inhibitor

CAS No.: 130495-35-1

MolecularFormula: C22H26N2O3.HCl

Molecular Weight: 402,92

Source: Synthetic

Purity: >98%

Solubility: Soluble to 100 mM in water

Appearance: White solid

PubChem CID: 104956

Scientific Background: SKF-96365 is a selective inhibitor of receptor mediated Ca2+ entry and voltage-gated Ca2+ entry (1). It has also been shown o inhibit cytochrome P-450 mediated reactions (1,2), and reversibly activates non-selective cation channels in human endotherlial cells (1,3).

References: 1. Leis H.J., et al. (1995) Br J Pharmacol. 114(3): 598-601.2. Sheets J.J., Mason J.I., Wise C.A. and Eastabrook R.W. (1986) Biochem Pharmacol. 35: 487-491.3. Schwarz G., Droogmans G. and Nilius B. (1994) Cell Calcium. 15: 45-54.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-305-25MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-305-25MG
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK