SLC12A3 Polyclonal Antibody, Rabbit

SLC12A3 Polyclonal Antibody, Rabbit
Artikelnummer
ELSE-AB-92031-60
Verpackungseinheit
60 µl
Hersteller
Elabscience Biotechnology

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Abbreviation: SLC12A3

Target Synonym: NCC;NCCT;TSC;SLC12A3

Conjugation: Unconjugated

UNIProt ID: P55017

Background: This gene encodes a renal thiazide-sensitive sodium-chloride cotransporter that is important for electrolyte homeostasis. This cotransporter mediates sodium and chloride reabsorption in the distal convoluted tubule. Mutations in this gene cause Gitelman syndrome, a disease similar to Bartter's syndrome, that is characterized by hypokalemic alkalosis combined with hypomagnesemia, low urinary calcium, and increased renin activity associated with normal blood pressure. This cotransporter is the target for thiazide diuretics that are used for treating high blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human SLC12A3

Dilution: WB 1:500-1:2000
Mehr Informationen
Artikelnummer ELSE-AB-92031-60
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-92031-60
Green Labware Nein
Verpackungseinheit 60 µl
Mengeneinheit STK
Reaktivität Human, Mouse (Murine), Monkey (Primate)
Klonalität Polyclonal
Methode Western Blotting
Isotyp IgG
Wirt Rabbit
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