Product Description: Spinoxin isolated from the venom of scorpion Heterometrus spinifer, is a 34-residue peptide neurotoxin cross-linked by four disulfide bridges. Spinoxin is a potent inhibitor of Kv1.3 potassium channel (IC50 = 63 nM), considering to be valid molecular targets in the diagnostics and therapy of various autoimmune disorders and cancers[1].
Applications: COVID-19-immunoregulation
Formula: C147H236N48O46S9
References: [1]Steve Peigneur, et al. Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning. Biochemistry. 2016 May 31;55(21):2927-35.
CAS Number: 752984-66-0
Molecular Weight: 3700.33
Compound Purity: 98.0
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Potassium Channel