SPTBN2 antibody (SPTBN2/2887R)

Clone Name: SPTBN2/2887R

Application Note: WB: 1-2 μg/ml. ICC/IF: 1-2 μg/ml. IHC-P: 1-2 μg/ml. FACS: 1-2 μg/million cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 271

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]

Uniprot ID: O15020

Antigen Species: Human

Immunogen: Recombinant human SPTBN2 fragment (aa356-475)

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: spectrin beta, non-erythrocytic 2

• Artikelnummer: GTX02717-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02717-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Flow Cytometry, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 6712
• Wirt: Rabbit