Product Type: Inhibitor
CAS No.: 179248-59-0
MolecularFormula: C22H19N3O3
Molecular Weight: 373,4
Source: Synthetic
Purity: ≥98% (TLC)
Solubility: Soluble in DMSO (5 mg/ml)
Appearance: Off-white solid
PubChem CID: 1474853
Scientific Background: SrcI1 is a potent and competitive dual site Src kinase inhibitor. It has been shown as a potent inhibitor of the Src and Lck kinase, as well as, VEGFR2 and c-fms. SrcI1 is cell permeable and can induce apoptosis.
References: 1. Bain, J., et al. (2007) Biochem. J. 408(3): 297–315. 2. Leung, E. L.H., et al. (2009) Mol. Cancer. Res: MCR. 7(6): 923–932.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.