st-Ht31 (ammonium)

Product Description: st-Ht31 ammonium is a membrane-permeable peptide inhibitor of protein kinase A (PKA) anchoring. st-Ht31 ammonium induces robust cholesterol/phospholipid efflux. st-Ht31 ammonium completely reverses foam cell formation and restores the metabolic health of macrophage[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C129H217N29O39.xNH3

References: [1]Ma L, et al. Ht31, a protein kinase A anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ATP-binding cassette transporter A1. J Biol Chem. 2011 Feb 4;286(5):3370-8. /[2]Rahamim Ben-Navi L, et al. A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa. Sci Rep. 2016 Nov 30;6:37922.

Molecular Weight: 2798.32 (free base)

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: PAK

• Artikelnummer: MEXHY-P2624A-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-P2624A-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK