Formulation: A crystalline solid
Formal Name: 4′-[[[1-(cyclopropylcarbonyl)-1,2,3,4-tetrahydro-7-quinolinyl]amino]sulfonyl]-[1,1′-biphenyl]-3-carboxamide
Purity: ≥98%
Formula Markup: C26H25N3O4S
Formula Weight: 475,6
Shelf life (days): 1460
CAS Number: 2210228-45-6
Notes: SU 0268 is an inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1; IC50 = 0.059 µM).{58865} It is selective for OGG1 over the DNA repair enzymes MTH1, dUTPase, NUDT16, ABH2, ABH3, and SMUG1 at 20 µM. SU 0268 (0.5 µM) inhibits OGG1 and increases the number of 8-oxoguanine DNA lesions in HeLa cell lysates.