Product Type: Inhibitor
CAS No.: 5812-07-7
MolecularFormula: C17H16N2O
Molecular Weight: 264,3
Source: Synthetic
Purity: ≥98% (HPLC)
Solubility: Soluble in DMSO (25 mg/ml)
Appearance: Orange solid
PubChem CID: 6450842
Scientific Background: SU 4312 is a potent and selective inhibitor of VEGFR and PDGFR tyrosine kinases, including VEGFR-2 (Flk-1, KDR).
References: 1. Zaman G.J., et al. (1999) Biochem. Pharm. 57(1): 57–64.2. Shimotake J., Derugin N., Wendland M., Vexler Z.S., & Ferriero D.M. (2010) Stroke. 41(2): 343–349. 3. Schultheiss C., et al. (2006) Angiogenesis. 9(2): 59–65.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.