SUN11602, CAS 704869-38-5

Formulation: A crystalline solid

Formal Name: 4-[[4-[[2-[(4-amino-2,3,5,6-tetramethylphenyl)amino]acetyl]methylamino]-1-piperidinyl]methyl]-benzamide

Purity: ≥98%

Formula Markup: C26H37N5O2

Formula Weight: 451,6

Shelf life (days): 1460

CAS Number: 704869-38-5

Notes: SUN11602 is a mimetic of FGF2, also known as basic FGF (bFGF).{62622} It protects against glutamate-induced toxicity in primary rat cortical neurons when used at concentrations of 0.1, 0.3, and 1 µM, an effect that can be reversed by the FGFR1 inhibitor PD 166866 (Item No. 22464). SUN11602 (1 µM) stimulates neurite outgrowth in primary rat hippocampal neurons.{62623} It reduces cognitive deficits induced by injection of aggregated amyloid-β (1-40) (Aβ40) and ibotenic acid (Item No. 14584) into the hippocampus in a rat model of Alzheimer’s disease when administered at a dose of 10 mg/kg.

• Artikelnummer: CAY36572-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36572-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK
• Methode: Reinstoffe