SYNGAP1 antibody (HL2292)

SYNGAP1 antibody (HL2292)
Artikelnummer
GTX638347-100
Verpackungseinheit
100 μl
Hersteller
GeneTex

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Clone Name: HL2292

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 148

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a Ras GTPase activating protein that is a member of the N-methyl-D-aspartate receptor complex. The N-terminal domain of the protein contains a Ras-GAP domain, a pleckstrin homology domain, and a C2 domain that may be involved in binding of calcium and phospholipids. The C-terminal domain consists of a ten histidine repeat region, serine and tyrosine phosphorylation sites, and a T/SXV motif required for postsynaptic scaffold protein interaction. The encoded protein negatively regulates Ras, Rap and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking to the postsynaptic membrane to regulate synaptic plasticity and neuronal homeostasis. Allelic variants of this gene are associated with intellectual disability and autism spectrum disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Uniprot ID: Q96PV0

Antigen Species: Human

Immunogen: Recombinant fragmemt of human SYNGAP1

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: synaptic Ras GTPase activating protein 1
Mehr Informationen
Artikelnummer GTX638347-100
Hersteller GeneTex
Hersteller Artikelnummer GTX638347-100
Verpackungseinheit 100 μl
Mengeneinheit STK
Reaktivität Mouse (Murine), Rat (Rattus)
Klonalität Recombinant
Methode Immunofluorescence, Western Blotting, Immunocytochemistry
Isotyp IgG
Human Gene ID 8831
Wirt Rabbit
Konjugat Unconjugated
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