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TAOK2, GST-tag Recombinant
TAOK2, GST-tag Recombinant
Artikelnummer
BPS40284
Verpackungseinheit
10 µg
Hersteller
BPS Bioscience
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Encompassing Amino Acids: 1-314
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Background: Thousand and one-amino acid protein kinase 2 (TAOK 2) is part of the stress-sensitive kinase cascade and activation of and binding to MKK3 by TAOK2 implicates it in the regulation of the p38-containing stress-responsive MAP kinase pathway (1). TAOK2 protein kinase activates p38 mitogen-activated protein kinase cascade in vitro and in cells by phosphorylating the MAP/ERK kinases MKK3 and MKK6. TAO2 may play an important role in the activation of specific intracellular signaling pathways that are unique to osmotic stress (2).
Description: Recombinant human TAOK2 (a.a. 1-314), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Genbank: NM_004783
Host Cell Line: Sf9 cells
Purity: ≥85%
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: Q9UL54
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Hutchison, M. et al: Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades. J. Biol. Chem. 1998; 273:28625-32.
2. Chen, Z. et al: TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors. J. Biol. Chem. 2003;278:22278-83.
Encompassing Amino Acids: 1-314
Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Background: Thousand and one-amino acid protein kinase 2 (TAOK 2) is part of the stress-sensitive kinase cascade and activation of and binding to MKK3 by TAOK2 implicates it in the regulation of the p38-containing stress-responsive MAP kinase pathway (1). TAOK2 protein kinase activates p38 mitogen-activated protein kinase cascade in vitro and in cells by phosphorylating the MAP/ERK kinases MKK3 and MKK6. TAO2 may play an important role in the activation of specific intracellular signaling pathways that are unique to osmotic stress (2).
Description: Recombinant human TAOK2 (a.a. 1-314), with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Format: Aqueous buffer solution
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Genbank: NM_004783
Host Cell Line: Sf9 cells
Purity: ≥85%
Storage Stability: At least 6 months at -80°C.
Tags: N-terminal GST-tag
Uniprot: Q9UL54
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Hutchison, M. et al: Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades. J. Biol. Chem. 1998; 273:28625-32.
2. Chen, Z. et al: TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors. J. Biol. Chem. 2003;278:22278-83.
| Artikelnummer | BPS40284 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 40284 |
| Green Labware | Nein |
| Verpackungseinheit | 10 µg |
| Mengeneinheit | STK |
| Wirt | Insect |
| Produktinformation (PDF) |
|
| MSDS (PDF) |
|
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