TCF3 / E2A antibody (HL1954)

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Clone Name: HL1954

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 68

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]

Uniprot ID: P15923

Antigen Species: Human

Immunogen: Recombinant fragment of human TCF3 / E2A

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: transcription factor 3

• Artikelnummer: GTX637791-S-25
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX637791-S-25
• Verpackungseinheit: 25 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Immunofluorescence, Western Blotting, Immunocytochemistry
• Isotyp: IgG
• Human Gene ID: 6929
• Wirt: Rabbit
• Konjugat: Unconjugated