TCL053, CAS 2361162-70-9

Formulation: A solution in ethanol

Formal Name: 2-(((4-(dimethylamino)butanoyl)oxy)methyl)-2-((((Z)-tetradec-9-enoyl)oxy)methyl)propane-1,3-diyl (9Z,9'Z)-bis(tetradec-9-enoate)

Purity: ≥98%

Formula Markup: C53H95NO8

Formula Weight: 874,3

Shelf life (days): 365

CAS Number: 2361162-70-9

Notes: TCL053 is an ionizable cationic amino lipid.{66116} It has been used in the generation of lipid nanoparticles (LNPs) and has a pKa value of 6.8. LNPs containing TCL053 and encapsulating mRNA encoding the Cas9 nuclease, in combination with LNPs containing TCL053 and encapsulating single-guide RNA (sgRNA) targeting the Rosa26 locus, have been used to induce CRISPR-mediated gene editing in the mouse gastrocnemius muscle.

• Artikelnummer: CAY37045-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37045-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe