Product Description: TCO-PEG12-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. TCO-PEG12-NHS ester is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
Applications: Cancer-programmed cell death
Formula: C40H70N2O18
References: [1]Leon S. FARHI, et al. Compositions and methods for high-sensitivity immunoassays. WO2018027221A1