Tertiapin LQ (trifluoroacetate salt)

Formulation: A solid

Formal Name: 2,2'-((2S,5S,8R,11S,14S,17S,20R,25R,28S,31S,34S,37S,40S,42aS,49S,52R)-11-((1H-indol-3-yl)methyl)-20-((2-(((S)-6-amino-1-(((S)-1,6-diamino-1-oxohexan-2-yl)amino)-1-oxohexan-2-yl)amino)-2-oxoethyl)carbamoyl)-5-(3-amino-3-oxopropyl)-14,17-bis(4-aminobutyl)-52-((S)-2-((S)-2-aminopropanamido)-4-methylpentanamido)-34,37,40-tri((S)-sec-butyl)-31-(3-guanidinopropyl)-2-isobutyl-3,6,9,12,15,18,26,29,32,35,38,41,42,48,51-pentadecaoxodotetracontahydro-1H,24H-25,8-(epiminoethanoiminopropanodithiomethano)pyrrolo[1,2-x][1,2]dithia[5,8,11,14,17,20,23,24,29,32,35,38,41]tridecaazacyclotetratetracontine-28,49-diyl)diacetamide, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C106H179N33O24S4 • XCF3COOH

Formula Weight: 2428

Shelf life (days): 1460

Notes: Tertiapin LQ is a peptide derivative of the honeybee venom peptide tertiapin and an inhibitor of inwardly rectifying potassium (Kir) channels.{69383,69384} It inhibits heteromultimeric potassium channels composed of G protein-activated inward rectifier potassium channel 1 (GIRK1) and GIRK4, also known as Kir3.1 and Kir3.4, respectively, as well as the inward-rectifier potassium channel 1 (Kir1.1). In vivo, tertiapin LQ suppresses the Purkinje cell pause response to a conditional stimulus in ferrets. {69384}

• Artikelnummer: CAY37496-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37496-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe