TFE3 antibody, N-term

Application Note: WB: 1-3μg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 62

Positive Control: The peptide used to generate this antibody is available for purchase (GTX89882-PEP).

Form: Liquid

Buffer (with preservative): TBS, 0.5% BSA, 0.02% Sodium azide.

Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot ID: P19532

Antigen Species: Human

Immunogen: Peptide with sequence SHAAEPARDGVEAS-C, from the N Terminus of the protein sequence according to NP_006512.2.

Purification: Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation: Unconjugated

Full Name: transcription factor binding to IGHM enhancer 3

• Artikelnummer: GTX89882-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89882-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 7030
• Wirt: Goat