Application Note: WB: 1:500 - 1:2000. ICC/IF: 1:100-1:500. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Uniprot ID: P36897
Antigen Species: Human
Immunogen: A synthesized peptide derived from human TGF beta Receptor I , corresponding to a region within the internal amino acids.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: transforming growth factor beta receptor 1