TIM-3 antibody (MSVA-366R) HistoMAX™

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Clone Name: MSVA-366R

Product Description: This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 33

Positive Control: Tonsil: A moderate to strong TIM-3 immunostaining should be seen in a significant fraction of T-cells, while only few TIM-3 positive cells are seen in the germinal centre and the mantle zone.

Negative Control: Tonsil: Epithelial cells should be negative.

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Uniprot ID: Q8TDQ0

Antigen Species: Human

Immunogen: Recombinant fragment of human TIM3 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: hepatitis A virus cellular receptor 2

• Artikelnummer: GTX04440-S-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX04440-S-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin)
• Isotyp: IgG
• Human Gene ID: 84868
• Wirt: Rabbit
• Konjugat: Unconjugated