TP Receptor (human) Polyclonal FITC Antibody

Formulation: 100 µl of fluorescein-labeled, peptide affinity-purified polyclonal antibody

Immunogen: Synthetic peptide from the C-terminal region of human TP receptor

Shelf life (days): 365

Notes: Thromboxane A2 (TXA2) is a potent vasoconstrictor and activator of platelet aggregation. The short half-life of TXA2 ensures local action whether generated by vascular endothelial cells or by platelets and confers physiologically beneficial or deleterious effects under inflammatory situations.{146,11131} TXA2 elicits its effects via a 7-transmembrane domain G protein-coupled receptor, the TP receptor.{6062} This receptor can also bind prostaglandin H2 and isoprostanes and was first cloned from human placenta and the platelet-like MEG-01 cell line.{11146,7729} The TP receptor is highly expressed in platelets and is relatively less abundant in tissues such as lung, kidney, brain, spleen, thymus, monocytes, uterus, and placenta.{3167,11368,2061,4311,8380,7235}

• Artikelnummer: CAY10012559-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10012559-100
• Green Labware: Nein
• Verpackungseinheit: 1 ea (100 µl)
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Flow Cytometry
• Wirt: Rabbit