Trehalose 6,6'-Dibehenate, CAS 66758-35-8

Formulation: A solid

Formal Name: 6-docosanoate 6-O-(1-oxodocosyl)-α-D-glucopyranosyl α-D-glucopyranoside

Purity: ≥95%

Formula Markup: C56H106O13

Formula Weight: 987,4

Shelf life (days): 1460

CAS Number: 66758-35-8

Notes: Trehalose 6,6'-dibehenate (TDB) is a synthetic glycolipid and derivative of trehalose-6,6′ dimycolate (TDM), also known as mycobacterial cord factor.{68365} It binds to a fusion protein of mouse macrophage-inducible C-type lectin (Mincle) and human IgG1 Fc in a cell-free assay when used at a concentration of 10 µg/ml. TDB (5 µg/ml) induces nitric oxide (NO) and G-CSF production in mouse bone marrow macrophages in a Mincle-dependent manner. Liposomes containing TDB and dimethyldioctadecylammonium (DDA; Item No. 26120) as adjuvants and the mycobacterial lipid antigens diacylated sulfoglycolipid (Ac2SGL) and phosphatidyl-myo-inositol dimannoside (PIM2) decrease spleen bacterial load and the number of lung and spleen lesions in a guinea pig model of M. tuberculosis infection.{36983}

• Artikelnummer: CAY37911-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37911-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: Reinstoffe