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Trichostatin A (TSA) , CAS 58880-19-6
Trichostatin A (TSA) , CAS 58880-19-6
Artikelnummer
BPS27102
Verpackungseinheit
5 mg
Hersteller
BPS Bioscience
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Biological Activity: TSA inhibited proliferation of eight breast carcinoma cell lines with mean ±SD IC50 of 124.4 ± 120.4 nM (range of 26.4 nM -308.1 nM). HDAC inhibitory activity of TSA was similar in all cell lines with mean ± SD IC50 of 2.4 ± 0.5 nM (range of 1.5 nM-2.9 nM), and TSA treatment resulted in pronouncing histone H4 hyperacetylation. TSA inhibited HDAC3 with IC50 of 0.9 nM using the BPS Bioscience Fluorogenic HDAC Assay Kit (Cat. #50061).
CAS Number: 58880-19-6
Description: Trichostatin A (TSA) is an antifungal antibiotic with cytostatic and differentiating properties in mammalian cell culture.
Format: White to beige powder.
Purity: ≥98% by HPLC
Solubility: Soluble to 10 mM in ethanol and to 50 mM in DMSO
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: Festuccia, C. et al. Endocr Relat Cancer 2009;16: 401-413
Biological Activity: TSA inhibited proliferation of eight breast carcinoma cell lines with mean ±SD IC50 of 124.4 ± 120.4 nM (range of 26.4 nM -308.1 nM). HDAC inhibitory activity of TSA was similar in all cell lines with mean ± SD IC50 of 2.4 ± 0.5 nM (range of 1.5 nM-2.9 nM), and TSA treatment resulted in pronouncing histone H4 hyperacetylation. TSA inhibited HDAC3 with IC50 of 0.9 nM using the BPS Bioscience Fluorogenic HDAC Assay Kit (Cat. #50061).
CAS Number: 58880-19-6
Description: Trichostatin A (TSA) is an antifungal antibiotic with cytostatic and differentiating properties in mammalian cell culture.
Format: White to beige powder.
Purity: ≥98% by HPLC
Solubility: Soluble to 10 mM in ethanol and to 50 mM in DMSO
Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Biosafety Level: Not applicable (BSL-1)
References: Festuccia, C. et al. Endocr Relat Cancer 2009;16: 401-413
| Artikelnummer | BPS27102 |
|---|---|
| Hersteller | BPS Bioscience |
| Hersteller Artikelnummer | 27102 |
| Green Labware | Nein |
| Verpackungseinheit | 5 mg |
| Mengeneinheit | STK |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
Immer für Sie da
Gernot Ensinger, M.Sc.
Laurent Haze
