Troponin I1/TnI1 Polyclonal Antibody, Rabbit

Abbreviation: Troponin I1/TnI1

Target Synonym: TNNI1;SSTNI;TNN1;troponin I1

Conjugation: Unconjugated

UNIProt ID: P19237

Background: Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human Troponin I1/TnI1

Dilution: WB 1:1000-1:2000

• Artikelnummer: ELSE-AB-92578-60
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92578-60
• Green Labware: Nein
• Verpackungseinheit: 60 µl
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit