TTLL12 Polyclonal Antibody, Rabbit

Abbreviation: TTLL12

Target Synonym: TTLL12; dJ526I14.2; tubulin tyrosine ligase like 12

Conjugation: Unconjugated

UNIProt ID: Q14166

Background: Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3. Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human TTLL12

Dilution: WB 1:500-1:2000

• Artikelnummer: ELSE-AB-92358-120
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-E-AB-92358-120
• Green Labware: Nein
• Verpackungseinheit: 120 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit