Tyrosinase-Related Protein-1 (TYRP-1) (Melanoma Marker)(TYRP1/3282), 0.2mg/mL

Description: Reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, with BSA

Concentration: 0.2 mg/mL

Storage buffer: PBS, 0.05% BSA, 0.05% azide

Product Origin: Animal

Clone: TYRP1/3282

Entrez Gene ID: 7306

Immunogen: A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)

• Artikelnummer: BTMBNUB3282-500
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUB3282-500
• Green Labware: Nein
• Verpackungseinheit: 500 uL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry
• Isotyp: IgG2b kappa
• Wirt: Mouse