Target Synonym: Th; TY3H; THP
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: TH (Tyrosine 3-hydroxylase), also known as Tyrosine 3-monooxygenase, is a 60-62 kDa member of the biopterin-dependent aromatic amino acid hydroxylase family of molecules. It is expressed by neurons of the dopamine and autonomic nervous system, plus the neuroendocrine cells of the adrenal medulla. TH is considered the rate limiting enzyme for catecholamine synthesis, and serves to catalyze the hydroxylation of L-tyrosine.
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4
Immunogen: Recombinant Mouse Tyrosine hydroxylase protein expressed by E.coli.
Dilution: WB 1:500-2000
Calculated MW: 55kDa
Observed MW: 55-60kDa