UHRF1 antibody (HL2287)

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Clone Name: HL2287

Light Chain: Kappa

Application Note: WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 90

Form: Liquid

Buffer (with preservative): PBS, no preservative.

Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12. [provided by RefSeq, Feb 2014]

Uniprot ID: Q96T88

Antigen Species: Human

Immunogen: Recombinant fragment of human UHRF1.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: ubiquitin like with PHD and ring finger domains 1

• Artikelnummer: GTX638342-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX638342-100
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Recombinant
• Methode: Immunohistochemistry (paraffin), Western Blotting
• Isotyp: IgG
• Human Gene ID: 29128
• Wirt: Rabbit
• Konjugat: Unconjugated