USP2 antibody

Application Note: WB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 68

Form: Liquid

Buffer (with preservative): PBS pH 7.3, 50% glycerol, 0.02% sodium azide.

Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Uniprot ID: O75604

Antigen Species: Human

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 200-430 of human USP2 (NP_004196.4).

Purification: Purified by affinity chromatography

Conjugation: Unconjugated

Full Name: ubiquitin specific peptidase 2

• Artikelnummer: GTX03925-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX03925-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 9099
• Wirt: Rabbit