UTX (KDM6A), C-term FLAG-tag Recombinant

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Encompassing Amino Acids: 1-1401

Applications: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Description: Human UTX, also known as KDM6A (GenBank Accession No. NM_021140) (a.a. 1-1401) with C-terminal FLAG-tag, MW = 155 kDa, expressed in Sf9 cells via a baculovirus expression system.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 3 mM DTT, 20% glycerol, and 80 µg/ml FLAG peptide

Genbank: NM_021140

Host Cell Line: Sf9 cells

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal FLAG-tag

Uniprot: O15550

Warnings: Avoid freeze/thaw cycles.

Biosafety Level: Not applicable (BSL-1)

References: 1. Greenfield, A., et al., (1998). Hum. Mol. Genet. 7(4):737-42.
2. Agger, K., et al., (2007). Nature. 449(7163):731-4.
1. Suzuki, T., et al., (2013). J Med Chem. 56(18):7222-31. Application Reference(s):
Identification of the KDM2/7 histone lysine demethylase subfamily inhibitor and its antiproliferative activity (2013)

• Artikelnummer: BPS50116
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 50116
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK
• Wirt: Insect