Product Description: Val-Cit-PAB-Exatecan (Val-Cit-PAB-DX8951) TFA is a agent-linker conjugate for ADC. Val-Cit-PAB-Exatecan TFA is composed of a DNA topoisomerase I DX-8951 (HY-13631) and a cathepsin cleavable ADC linker[1].
Applications: Cancer-programmed cell death
Formula: C45H50F4N8O11
References: [1]Thomas A, et al. Antibody-drug conjugates for cancer therapy. Lancet Oncol. 2016 Jun;17(6):e254-e262.
CAS Number: 2928571-44-0
Molecular Weight: 954.92
Compound Purity: 99.23
Research Area: Cancer
Target: Drug-Linker Conjugates for ADC;Topoisomerase