Vatalanib Dihydrochloride, CAS 212141-51-0

VEGFR inhibitor

Product Type: Inhibitor

CAS No.: 212141-51-0

MolecularFormula: C20H17Cl3N4

Molecular Weight: 419,7

Source: Synthetic

Purity: ≥96%

Solubility: Soluble in DMSO (30 mg/ml), ethanol (10 mg/ml) with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 10-20 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility.Also soluble in methanol, and water ( ≥10 mg/ml )

Appearance: Solid

PubChem CID: 22386467

Scientific Background: Vatalanib Dihydrochloride is an inhibitor of Flk, c-Kit and PDGFR-β. It has been shown to inhibit VEGFR-dependent tumor angiogenesis and EGFR- and RET-dependent tumor cell proliferation and survival.

References: 1. Herbst R.S., Heymach J.V., O'Reilly M. S., Onn A., & Ryan A.J. (2007) Expert Opin. Invest. Drugs. 16(2): 239–249.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-484-50MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-484-50MG
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK