Vildagliptin, CAS 274901-16-5

Anti-diabetic agent

Product Type: Inhibitor

CAS No.: 274901-16-5

MolecularFormula: C17H25N3O2

Molecular Weight: 303,4

Source: Synthetic

Purity: >98% (HPLC); NMR (Conforms)

Solubility: May be dissolved in DMSO (45 mg/ml); or DMF (20 mg/ml); or ethanol (20 mg/ml)

Appearance: White powder

PubChem CID: 11077541

Scientific Background: Vildagliptin is a potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that cleaves glucagon-like peptide 1 (GLP-1) (1). Delaying the degradation of GLP-1 extends the action of insulin and suppresses the release of glucagon which results in reduction in elevated blood glucose levels (hyperglycemia) (2). It is a clinically useful antidiabetic agent.

References: 1. B Balas et al., (2007) J. Clin. Endocrinol. Metab. 92:1249.2. B Ahren et al., (2004) J. Clin. Endocrinol. Metab. 89:2078.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-567-20MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-567-20MG
• Green Labware: Nein
• Verpackungseinheit: 20 mg
• Mengeneinheit: STK