Vimentin(VM452), 1mg/mL

Description: This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP's) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: VM452

Entrez Gene ID: 7431

Immunogen: Recombinant full-length human vimentin protein

Verified AB Applications: Flow (intracellular) (verified)/IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: Flow, intracellular (verified)/IHC, FFPE (verified)/WB (verified)

• Artikelnummer: BTMBNUM0452-50
• Hersteller: Biotium
• Hersteller Artikelnummer: BNUM0452-50
• Green Labware: Nein
• Verpackungseinheit: 50 uL
• Mengeneinheit: STK
• Reaktivität: Human, Pig (Porcine), Cat (Feline), Dog (Canine), Cow (Bovine), Chicken, Goat (Caprine)
• Klonalität: Monoclonal
• Methode: Western Blotting, Flow Cytometry, Immunohistochemistry
• Isotyp: IgG1
• Wirt: Mouse