Product Description: WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide. WLSEAGPVVTVRALRGTGSW-expressing exosomes can improve specific uptake by cardiomyocytes, decrease cardiomyocyte apoptosis, and enhance cardiac retention following intramyocardial injection in vivo[1][2].
Applications: Neuroscience-Neurodegeneration
Formula: C97H152N28O27
References: [1]McGuire MJ, et, al. In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo. J Mol Biol. 2004 Sep 3;342(1):171-82./[2]Mentkowski KI, et, al. Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo. Sci Rep. 2019 Jul 11;9(1):10041.
CAS Number: 771479-86-8
Molecular Weight: 2142.42
Compound Purity: 96.26
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Apoptosis