Wnt-C59 , CAS 1243243-89-1

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Background: Wnt-C59 prevents palmitoylation of Wnt proteins by Porcupine (a membrane-bound O-acyltransferase), thereby blocking Wnt protein secretion and activity, similar to Wnt inhibitors IWP-2, IWP-3 and IWP-4. But Wnt-C59 is more potent and selective, and has better chemical/physical properties, and is more suitable for in vitro/in vivo studies.

CAS Number: 1243243-89-1

Description: Wnt-C59 is a very potent and highly selective Wnt signaling antagonist with an IC50 ~ 74 pM in the Wnt signaling reporter assay.

Solubility: Soluble in DMSO

Storage Stability: Store at or below -20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Target: Porcupine

Biosafety Level: Not applicable (BSL-1)

References: Proffitt KD, et al. Cancer Res. 2013 Jan 15;73(2):502-7.

• Artikelnummer: BPS27780-1
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 27780-1
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK