XL228, CAS 898280-07-4

Description: XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).

CAS Number: 898280-07-4

Formula: C22H31N9O

Molecular Weight: 437,54

References: Cortes J, et al. Preliminary Clinical Activity in a Phase I Trial of the BCR-ABL/IGF- 1R/Aurora Kinase Inhibitor XL228 in Patients with Ph++ Leukemias with Either Failure to Multiple TKI Therapies or with T315I Mutation. Blood 2008 112:3232

• Artikelnummer: TGMT17267-2mg
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T17267-2mg
• Verpackungseinheit: 2 mg
• Mengeneinheit: STK