ZAP70 antibody (ZAP70/4040R)

Clone Name: ZAP70/4040R

Application Note: IHC-P: 1-2 μg/ml. ELISA: 2-4 μg/ml (for coating). *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 70

Form: Liquid

Buffer (with preservative): 1mM PBS, 0.05% BSA, 0.05% Sodium azide.

Concentration: 200 μg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot ID: P43403

Antigen Species: Human

Immunogen: Synthetic peptide corresponding to human ZAP-70 residues within aa200-350

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: zeta chain of T cell receptor associated protein kinase 70

• Artikelnummer: GTX02746-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02746-100
• Green Labware: Nein
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunohistochemistry (paraffin), ELISA
• Isotyp: IgG
• Human Gene ID: 7535
• Wirt: Rabbit