Beta Defensin-1, mouse recombinant (rHuBD-1)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 4100 D

Purity: >97%

Description: Mouse recombinant BD 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 37 amino acids and having a molecular mass of 4.1 kDa. The Defensin family are highly similar in their protein sequence and are microbicidal and cytotoxic peptides made by neutrophils. Beta Defensin-1 is an antimicrobial peptide having the resistance of epithelial surfaces to microbial colonization. Beta Defensin-1 has close proximity to Defensin Alpha-1 and has been implicated in the pathogenesis of cystic fibrosis. Skin of patients having atopic dermatitis patients and mycosis fungoides (non-lesional and lesional) show lower human Beta Defensin-1 mRNA expression and higher human Beta Defensin-2 and human Beta Defensin-3 mRNA expression. Beta Defensin is highly expressed by epithelial cells. Beta-defensin 1 may play a role in the pathogenesis of severe sepsis.

• Artikelnummer: BOL97410.5
• Hersteller: Biomol
• Hersteller Artikelnummer: 97410.5
• Green Labware: Nein
• Verpackungseinheit: 5 µg
• Mengeneinheit: STK
• Reaktivität: Mouse (Murine)
• Human Gene ID: 13214
• Wirt: Escherichia Coli