Beta Defensin-4, rat recombinant (rrBD-4)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 4400 D

Purity: >97%

Description: Rat recombinant BD-4 produced in E.coli is a single, non-glycosylated polypeptide chain containing 41 amino acids and having a molecular mass of 4.4kDa. Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The Alpha defensins are differentiated from the Beta-defensins by the pairing of their 3 disulfide bonds. 4 human Beta-defensins have been identified to date, BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and, in the case of BD-1 (36), a propeptide region. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta-Defensins are 3-5 kDa peptides ranging in size from 33-47 amino acid residues.

• Artikelnummer: BOL97415.20
• Hersteller: Biomol
• Hersteller Artikelnummer: 97415.20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK
• Reaktivität: Rat (Rattus)
• Human Gene ID: 64389
• Wirt: Escherichia Coli