Description: Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 80 amino acids. Btc is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.