Epstein Barr Virus Induced 3, human recombinant, (rHuEBI3)

Kategorie: Cytokines

Formulation: purified

Storage: -20°C

Purity: 90%

Description: Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines. (www.uniprot.org). Human recombinant EBI produced in E.coli is a single, non-glycosylated, polypeptide chain containing 209 amino acids fragment (21-229) having a molecular weight of 23.3 kDa.

• Artikelnummer: BOL97374.1
• Hersteller: Biomol
• Hersteller Artikelnummer: 97374.1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Reaktivität: Human
• Wirt: Escherichia Coli