Fibroblast Growth Factor-23, human recombinant (rHuFGF23)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 22500 D

Purity: >95%

Description: Human recombinant Fibroblast Growth Factor-23 produced in E.coli is a single, non-glycosylated polypeptide chain containing a total of 228 amino acids and having a molecular mass of 22.5kDa. FGF-23 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-23 inhibits renal tubular phosphate transport. The FGF-23 gene was identified by its mutations associated with autosomal dominant hypophosphatemic rickets (ADHR), an inherited phosphate wasting disorder. Abnormally high level expression of FGF-23 was found in oncogenic hypophosphatemic osteomalacia (OHO), a phenotypically similar disease caused by abnormal phosphate metabolism. FGF-23 mutations have also been shown to cause familial tumoral calcinosis with hyperphosphatemia.

• Artikelnummer: BOL97445.20
• Hersteller: Biomol
• Hersteller Artikelnummer: 97445.20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Human Gene ID: 8074
• Wirt: Escherichia Coli