Description: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing amino acids 148-240 and a his-tag.