Interferon Gamma-Inducible protein 30, His tag, human recombinant (rHuIFI30-His)

Kategorie: Cytokines

Formulation: solution

Storage: -20°C

Weight: 22500 D

Purity: >90%

Description: IFI30 human recombinant produced in E. coli is a single polypeptide chain containing 199 amino acids (58-232) and having a molecular mass of 22.5 kDa. IFI30 is fused to a 24 amino acid His-tag at N-terminus. Gamma-interferon-inducible lysosomal thiol reductase (IFI30), is a part of the GILT family. IFI30 is a lysosomal thiol reductase which at low pH is capable of decreasing protein's disulfide bonds. IFI30 is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. Also, IFI30 plays an important role in MHC class II-restricted antigen processing. IFI30 facilitates the generation of MHC class II-restricted epitopes from disulfide bond-containing antigen by the endocytic reduction of disulfide bonds and also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation.

• Artikelnummer: BOL97629.2
• Hersteller: Biomol
• Hersteller Artikelnummer: 97629.2
• Green Labware: Nein
• Verpackungseinheit: 2 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Human Gene ID: 10437
• Wirt: Escherichia Coli