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Interleukin-13, 109 amino acids, rat recombinant (rrIL-13)
Interleukin-13, 109 amino acids, rat recombinant (rrIL-13)
Artikelnummer
BOL97602.2
Verpackungseinheit
2 µg
Hersteller
Biomol
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Kategorie: Cytokines
Formulation: lyophilized
Storage: -20°C
Weight: 11900 D
Purity: >95%
Description: Rat recombinant Interleukin-13 produced in E.coli is a single, non-glycosylated polypeptide chain containing 109 amino acids and having a molecular mass of 11.9 kDa. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL-3, IL-5, IL-4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-4.
Formulation: lyophilized
Storage: -20°C
Weight: 11900 D
Purity: >95%
Description: Rat recombinant Interleukin-13 produced in E.coli is a single, non-glycosylated polypeptide chain containing 109 amino acids and having a molecular mass of 11.9 kDa. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL-3, IL-5, IL-4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-4.
| Artikelnummer | BOL97602.2 |
|---|---|
| Hersteller | Biomol |
| Hersteller Artikelnummer | 97602.2 |
| Green Labware | Nein |
| Verpackungseinheit | 2 µg |
| Mengeneinheit | STK |
| Reaktivität | Rat (Rattus) |
| Human Gene ID | 116553 |
| Wirt | Escherichia Coli |
| Produktinformation (PDF) | Download |
| MSDS (PDF) |
|
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Gernot Ensinger, M.Sc.
Laurent Haze
