Interleukin-13, Rhesus Macaque recombinant (rrmIL-13)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 12600 D

Purity: >97%

Description: Rhesus Macaque recombinant IL 13 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 114 amino acids and having a molecular mass of 12.6kDa. IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B-cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL-3, IL-5, IL-4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL-4.

• Artikelnummer: BOL97595.10
• Hersteller: Biomol
• Hersteller Artikelnummer: 97595.10
• Green Labware: Nein
• Verpackungseinheit: 10 µg
• Mengeneinheit: STK
• Reaktivität: Rhesus Monkey (Primate)
• Human Gene ID: 574325
• Wirt: Escherichia Coli