Interleukin-16, rhesus macaque recombinant (rrmIL-16)

Kategorie: Cytokines

Formulation: lyophilized

Storage: -20°C

Weight: 12500 D

Purity: >98%

Description: Rhesus Macaque recombinant IL-16 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 121 amino acids and having a molecular mass of 12.5kDa. IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of IL-16 is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. IL-16 functions exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Two transcript variants encoding different isoforms have been found for this gene. IL-16 stimulates a migratory response in cd4+ lymphocytes, monocytes, and eosinophils. Also induces t-lymphocyte expression of interleukin 2 receptor, ligand for cd4.

• Artikelnummer: BOL97496.2
• Hersteller: Biomol
• Hersteller Artikelnummer: 97496.2
• Green Labware: Nein
• Verpackungseinheit: 2 µg
• Mengeneinheit: STK
• Reaktivität: Rhesus Monkey (Primate)
• Human Gene ID: 574100
• Wirt: Escherichia Coli